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2022

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12.21.22 Welcome Suruchi! Welcome to Suruchi Poddar who joins us as a postdoctoral associate. Suruchi comes to us most recently from the University of Central Florida and brings with her a background in devices and microfluidics among others. She will be focused on hyaluronan analysis with nanopores.

12.16.22 Farewell, Bhoomija PhD student Bhoomija has opted to leave the program to take an a new challenge in intellectual property at the VA in Houston, TX, where she has family ties. We are sad to see her go but wish her well in this next chapter. 

10.3.22 Komal baby shower We celebrated Komal's forthcoming first child with a surprise shower. We will miss her while she's on maternity leave for a few weeks and wish her the absolute best as she and her husband experience all the ups and downs. Looking forward to seeing you on the other side!

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9.30.22 Felipe successfully defends Felipe defended his thesis "Use of Solid-State Nanopores for the Characterization and Quantification of Hyaluronic Acid (HA) as a Disease Biomarker in Biological Fluids and Tissues" today, becoming the latest PhD from our lab. His presentation went great and he passed unanimously with minimal revisions to his document. He will now transition to industry. Congratulations, Felipe!

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8.5.22 Welcome Max Lee We welcome our newest member, Maxwell Lee! Max joins us after completing his BS in Biomedical Engineering at the University of Michigan and will be focusing on nanopore measurements, especially emerging collaborative work with with the CBMM at Kansas University. Happy to have you here, Max!

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7.10.22-7.15.22 Adam presents at Gordon Research Conference Adam gave an invited presentation on the group's hyaluronan analysis work at the Proteoglycans GRC in New Hampshire. It was a great experience spending time with the glycan community and getting to hear about this new (to us) area of research!

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7.5.22 New paper in Nano Research A new paper by PhD student Ian Wadsworth is now available online in Nano Research! It describes the effect of both symmetric and asymmetric salt conditions on the selective nanopore assay we developed to detect nucleic acid biomarkers, achieving a 2-order improvement in sensitivity while maintaining a high selectivity. This paper is part of a special issue celebrating the eighth annual Nano Research award to friend of the lab and Adam's postdoc PI Prof. Dr. Cees Dekker. Congratulations to Ian on the paper and to Cees on the award!

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7.1.22 Dariya now on PhD track MS student Dariya has decided to switch over to the BME department's PhD track instead, allowing her to stay around for a while! She will continue working on regenerative medicine topics, but will now have the opportunity to expand the scope of her project. Congratulations, Dariya!

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6.11.22-6.18.22 Adam presents at nanopore conference in Croatia Adam attended and presented at the "From Solid State to BioPhysics X: From Basic to Life Sciences" conference in Cavtat, Croatia. It was an incredible setting with a great agenda inside and outside of the conference rooms and gave the opportunity for a lot of the nanopore community to see each other. Thank you to the organizers for the invitation to take part!

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5.31.22 Welcome to our new REU summer student The lab welcomes Carla Rodriguez as our 2022 REU (Research Experience for Undergraduates) student! Carla is a sophomore at Wake Forest University and is working with our nanopore team this summer on a range of measurements involving HA. 

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5.27.22 Ian presents at CBMM meeting in KS Ian Wadsworth presented his poster "Effects of asymmetric and asymmetric salt conditions on a selective nanopore assay" at the all-hands meeting for the CBMM at Kansas University. Great poster and great chance to get the whole team together for the first time in a long time! 

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5.14.22 Congratulations, Robyn! One more congratulations as Robyn is hooded and officially graduates! We all wish her the best of luck as she transitions to the next phase of her career in Raleigh.

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5.10.22 Robyn wins award at SBES Symposium Robyn presented her MS work at the annual research symposium of the Virginia Tech-Wake Forest School of Biomedical Engineering and Sciences and was awarded Best Oral Presentation in the Cancer Engineering session! This award was based on votes from faculty and students and was presented in the closing ceremony. Congratulations, Robyn!

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4.18.22 New webinar on solid-state nanopores Adam delivered a webinar entitled "An Introduction to Solid-State Nanopore Technology: Fabrication, Fundamentals, and Applications". This was the first of a series of webinar offered through the Center of BioModular Multi-Scale Systems for Precision Medicine (CBM2), a NIBIB-funded Biotechnology Resource Center lead by Steve Soper at the University of Kansas and for which Adam is a co-investigator. The webinar was recorded and can be viewed here.

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3.30.22 Robyn defends MS thesis Robyn successfully defended her Masters thesis entitled "Advancing T Cell Mediated Therapy Using 3D Tumor Organoids and Microfluidics" with a very well designed and delivered presentation. Congratulations, Robyn!

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3.28.22 Damian joins the lab Damian Hutchins, who has been working with Robyn this semester, has now officially joined as a PhD student. He will be co-advised by Shay Soker (WFIRM) and Adam and will continue work on an adaptive immunity project involving microfluidics and patient-derived tumor tissue. Welcome, Damian!

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3.16.22 Hyaluronan paper published in Scientific Reports Felipe's new paper on hyaluronan analysis is now available in Scientific Reports. It describes a large, systematic exploration of experimental variables impacting the sensitivity and resolution of HA measurements with solid-state nanopores, including applied voltage, nanopore diameter, and buffer salt conditions. This is a continuation of our collaborative work with Ellie Rahbar here at Wake and Paul DeAngelis at Oklahoma. 

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2.22.22 New review article on hyaluronan methods A new review article from the lab has been accepted for publication by the American Journal of Physiology Cell Physiology. In it, we describe techniques for the isolation/extraction of physiological hyaluronan as well as technologies for analyzing it. This paper is a collaboration with Ellie Rahbar here at Wake, Paul DeAngelis at Oklahoma, and Mary Cowman at NYU. Congrats to all authors!

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